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Facile New Syntheses of Substituted Benzhydryl Derivatives Using Trichloroacetimidate C-C Bond Formation Method

Received: 17 November 2014     Accepted: 26 November 2014     Published: 5 December 2014
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Abstract

An improved syntheses of substituted benzhydryl derivatives has been developed. This facile two-step procedure involves C-C bond formation from O-diphenylmethyltrichloroacetimidate and C-nucleophiles in the presence of TMSOTf. The C-nucleophiles include arenes, alkenes, alkene silylated C-nucleophiles and trimethylsiloxy alkenes to give a series substituted benzhydryl derivatives in excellent yields.

Published in Science Journal of Chemistry (Volume 2, Issue 5)
DOI 10.11648/j.sjc.20140205.11
Page(s) 38-43
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2014. Published by Science Publishing Group

Keywords

Trichloroacetimidate Method, C-C Bond Formation, C-Nucleophiles, Bezhydryl Derivatives

References
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Cite This Article
  • APA Style

    Walid Fathalla. (2014). Facile New Syntheses of Substituted Benzhydryl Derivatives Using Trichloroacetimidate C-C Bond Formation Method. Science Journal of Chemistry, 2(5), 38-43. https://doi.org/10.11648/j.sjc.20140205.11

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    ACS Style

    Walid Fathalla. Facile New Syntheses of Substituted Benzhydryl Derivatives Using Trichloroacetimidate C-C Bond Formation Method. Sci. J. Chem. 2014, 2(5), 38-43. doi: 10.11648/j.sjc.20140205.11

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    AMA Style

    Walid Fathalla. Facile New Syntheses of Substituted Benzhydryl Derivatives Using Trichloroacetimidate C-C Bond Formation Method. Sci J Chem. 2014;2(5):38-43. doi: 10.11648/j.sjc.20140205.11

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  • @article{10.11648/j.sjc.20140205.11,
      author = {Walid Fathalla},
      title = {Facile New Syntheses of Substituted Benzhydryl Derivatives Using Trichloroacetimidate C-C Bond Formation Method},
      journal = {Science Journal of Chemistry},
      volume = {2},
      number = {5},
      pages = {38-43},
      doi = {10.11648/j.sjc.20140205.11},
      url = {https://doi.org/10.11648/j.sjc.20140205.11},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.sjc.20140205.11},
      abstract = {An improved syntheses of substituted benzhydryl derivatives has been developed. This facile two-step procedure involves C-C bond formation from O-diphenylmethyltrichloroacetimidate and C-nucleophiles in the presence of TMSOTf. The C-nucleophiles include arenes, alkenes, alkene silylated C-nucleophiles and trimethylsiloxy alkenes to give a series substituted benzhydryl derivatives in excellent yields.},
     year = {2014}
    }
    

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  • TY  - JOUR
    T1  - Facile New Syntheses of Substituted Benzhydryl Derivatives Using Trichloroacetimidate C-C Bond Formation Method
    AU  - Walid Fathalla
    Y1  - 2014/12/05
    PY  - 2014
    N1  - https://doi.org/10.11648/j.sjc.20140205.11
    DO  - 10.11648/j.sjc.20140205.11
    T2  - Science Journal of Chemistry
    JF  - Science Journal of Chemistry
    JO  - Science Journal of Chemistry
    SP  - 38
    EP  - 43
    PB  - Science Publishing Group
    SN  - 2330-099X
    UR  - https://doi.org/10.11648/j.sjc.20140205.11
    AB  - An improved syntheses of substituted benzhydryl derivatives has been developed. This facile two-step procedure involves C-C bond formation from O-diphenylmethyltrichloroacetimidate and C-nucleophiles in the presence of TMSOTf. The C-nucleophiles include arenes, alkenes, alkene silylated C-nucleophiles and trimethylsiloxy alkenes to give a series substituted benzhydryl derivatives in excellent yields.
    VL  - 2
    IS  - 5
    ER  - 

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Author Information
  • Department of Mathematics and Physics, Faculty of Engineering, Port-Said University, Port Said, Egypt

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